Lactogenesis in the rat. Changes in metabolic parameters at parturition

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Progesterone and the metabolic control of the lactose biosynthetic pathway during lactogenesis in the rat.

1. Lactogenesis was initiated in pregnant rats by ovariectomy, thereby causing progesterone withdrawal, after which the mammary tissue was analysed for contents of enzymes and metabolites concerned with the biosynthesis of lactose. 2. Lactose synthesis increased about 126-fold with little or no accompanying change in the contents of most metabolic intermediates or in the adenine nucleotide ener...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1967

ISSN: 0306-3283

DOI: 10.1042/bj1050995